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Pseudomonas aeruginosa Biofilm Structure, Behavior and Hydrodynamics: Author: Purevdorj-Gage, Boloroo; Date: 2004-12-15; Program: Microbiology; Abstract: Biofilm formation by bacterial pathogens is an important factor in the progression and treatment of many infectious diseases. Biofilm structural development is a dynamic process dependent on many cellular and environmental parameters including Quorum Sensing (QS) and hydrodynamics. Since QS is dependent on a threshold autoinducer concentration, it was hypothesized that the flow dynamics in the bulk fluid surrounding the biofilm would play an important role in expression of QS and the genes that are under its control. In order to investigate the relative contribution of hydrodynamics and QS on ...; Download File | View full details