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Comprehensive Transcriptional Profiling of γδ T Cells
Author: Graff, Jill Christin
Date: 2005-12-15
Program: Veterinary Molecular Biology
Abstract: γδ T cells have been conserved since the adaptive immune system arose, yet their importance is still unclear. In an attempt to compensate for the lack of a broad knowledge-base of γδ T cells across species, global analyses of γδ T cell transcriptomes have been performed using serial analysis of gene expression (SAGE). Twelve new SAGE libraries were generated from the following bovine lymphocyte populations: magnetic bead-sorted blood γδ T cells, spleen γδ T cells and enr...
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